Sodium Carboxymethyl Cellulose
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 Pure Grade
Pharmaceutical Grade
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Croscarmellose Sodium
Microcrystalline Cellulose
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Sodium Carboxymethyl Cellulose - Grade : Pure / Food |
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White to Off White Powder
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Solubility |
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Easily Dispersed in Water |
Identification |
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Comply with USP Tests A. B. C. |
pH |
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6.0 - 8.0 |
LDO |
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Max. 10% |
Assay |
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6.5 To 9.5 % Na on Dried Basic |
Viscosity at 25o C |
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As Desired |
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Grade |
Solution Conc. On Dry Basis |
Viscosity at 25o C ( Brook Field LVT ) |
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25 - 100 cps. |
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25 - 50 cps. |
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80 - 150 cps. |
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250 - 350 cps. |
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600 - 1200 cps. |
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300 - 600 cps |
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Sodium Carboxymethyl Cellulose -Grade : Pharma Grade ( Standards of IP 96 ) |
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White or almost White, Granular Powder
Odourless or almost Odourless
Hygroscopic.
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Solubility |
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Conforms as per IP |
Identification |
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Tests A. B. C. |
pH |
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6.0 - 8.0 |
Clarity of Solution |
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Not more opalescent than standard OS4 |
Colour of Solution |
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Not more intensity coloured than YS6. |
Arsenic |
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Less than 1 ppm. |
Heavy Metals |
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Not more than 20 ppm. |
Chloride
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10 ml. of solun. A Complies with the limit
Test for Chlorides. |
Sulphated Ash |
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Between 20 and 33.3% |
LDO |
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Not more than 10% |
Assay |
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6.5% To 10.8 % Sodium on Dried Basic |
Apparant Viscosity |
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Between 75 and 140% of the declared
valued. |
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Grade |
Solution Conc. On Dry Basis |
Viscosity at 25o C ( Brook Field LVT ) |
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25 - 100 cps. |
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25 - 50 cps. |
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80 - 150 cps. |
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250 - 350 cps. |
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600 - 1200 cps. |
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300 - 600 cps |
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Sodium Carboxymethyl Cellulose ( CMC ) |
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Sodium Carboxy Methyl Cellulose is an anionic water soluble polymer derived from cellulose.
It is odourless, tasteless and nontoxic. It has the following properties making it useful in a wide variety of applications.
1. Easy Solubility in cold and hot water
2. Fine film forming properties
3. Resistance to oil greases and solvents
4. Better thickening action
5. Physiological inertness
6. Anionic character
7. Binding properties
8. Suspending characteristics
9. Gives transparent film
10. Acts as a protective colloid reducing water losses
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1. Textiles
2. Textile Finishing
3. Textile Printing
4. Detergents
5. Insecticides
6. Oil Well Drilling Operations
7. Paper Industry
8. Leather
9. Paints
10. Foundry
11. Ceramic Industries
12. Welding Electrodes
13. Pencils & Crayons
14. Explosives
15. Plywood
16. Food Industry
17. Cosmetic Industry
18. Pharmaceutical Industry
19. Adhesive Industry |
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Sodium Carboxymethyl Cellulose ( CMC ) |
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Description : -
Croscarmellose Sodium is a cross linked polymer of Carboxymethyl Cellulose Sodium. Cross an insoluble, hydrophilic, highly absorbent material, rsulting in excellent swelling properties fibrous nature gives it excellent water wicking capacities. Croscarmellose Sodium provides dissolution and disintegration characteristics, thus improving bioavailability of formulation.
Applications : -
Croscarmellose Sodimu is used in oral pharmaceutical formulations as a disintegrant for and Granules.
In tablet formulations Croscarmellose Sodium may be used in both direct-compassion and processes.
When used in wet gradations the Croscarmellose Sodium is best added in boat the wet ar the process (intra and extra granularly) so that the wicking and swelling ability of the disint utilised.
Concentrations of up as 5% W/W of Croscarmellose Sodium may be used as a tablet disinte normally 2% W/W is used in tablets prepared by direct compression and 3% W/W in tablet wet granulation process.
Stability And Storage Conditions : -
Croscarmellose Sodium is a stable though hygroscopic material.
Otscarmdkse Sodium snould be stored in a well closed container in a cool, dry place.
Specifications : -
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pH
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Between 5 and 7. |
LOD |
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NMT 10%. |
Sodium Chloride and Sodium Glycollate |
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NMT 0.5%.
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Heavy Metals |
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NMT 10 PPM. |
Degree of Substitution |
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Between 0.6 and 0.85. |
Content of Water Soluble material |
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Between 10 and 30 ml. |
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